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Polynucleotide Injections: Do They Actually Work for Pimples Scar Therapy?

Admin by Admin
March 30, 2025
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Polynucleotide Injections: Do They Actually Work for Pimples Scar Therapy?
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You’ve tried all the things. Serums, peels, even these fancy rollers. However these pimples scars? They only received’t budge. The battle towards pimples scars is actual. As somebody with acne-prone, oily pores and skin, I do know firsthand that it’s a irritating, ongoing battle that may appear endless. So each time one thing new comes out claiming to work as an pimples scar remedy, it’s arduous to not be curious. For those who’ve heard whispers about polynucleotide injections, you’re hoping they could be the breakthrough you’ve been ready for. However with so many remedies failing to ship, skepticism is comprehensible. Let’s discover the analysis and see if PN injections can genuinely make a distinction as an pimples scar remedy.

What Are Polynucleotide Injections?

Polynucleotides are DNA and RNA items. In your physique, they assist your pores and skin restore itself. Within the clinic, dermatologists use polynucleotide injections, additionally known as salmon sperm facials, to enhance pores and skin texture, scale back wrinkles, and hydrate pores and skin. They may additionally assist with redness. This makes them common for folks wanting higher pores and skin.

Most dermatologists use polynueclotide injections to assist enhance collagen and restore pores and skin as an anti-aging remedy. This means they might assist with pimples scars. Pimples scars occur when collagen and pores and skin tissue are broken. However do polynucleotide injections actually assist as an pimples scar remedy?

The Science Behind Polynucleotide Injections for Pores and skin Enchancment: Can the Salmon Sperm Facial Act as an Pimples Scar Therapy?

So, what does the science say about how these polynucleotide injections truly work in your pores and skin? Most research have targeted on issues like pores and skin texture, hydration, how stretchy your pores and skin is, and whether or not they can scale back wrinkles. Principally, they’re taking a look at common pores and skin enhancements and anti-aging. They’ve discovered that polynucleotide injections can assist your pores and skin really feel extra elastic and hydrated. Consider it as giving your pores and skin a giant drink of water, which may make it look smoother. Moreover, individuals who have tried these remedies are typically fairly pleased with how their general pores and skin high quality improves. In fact, everybody’s expertise was somewhat completely different relying on their age and what pores and skin points they’re coping with.

There may be additionally some proof that PN injections will help with facial redness. However in the case of these deeper pimples scars, the sort that actually dig into your pores and skin, the analysis simply isn’t there but. We nonetheless want extra research to know in the event that they make a big distinction. Lastly, a research confirmed that fillers mixed with polynucleotides can enhance pores and skin thickness, tone, and wrinkles. That implies they’ve some potential for pores and skin restore. However once more, it’s extra about common pores and skin enchancment and fewer a couple of focused pimples scar remedy.

So Do Polynucleotide Injections Work for Pimples Scars?

All of those research present that polynucleotide injections can enhance pores and skin. However there’s little direct proof that they’re an efficient pimples scar remedy. Pimples scars usually imply much less collagen and uneven pores and skin. Remedies that enhance collagen (like microneedling and lasers) are extra tried and true than polynucleotide injections. So, whereas a salmon sperm facial could be a great possibility to assist with pores and skin restore and hydration, it isn’t but a go-to remedy for deep pimples scars.

Evaluating Polynucleotide Injections to Different Standard Pimples Scar Remedies

For those who’re fascinated about polynucleotide injections for pimples scars, evaluate them to different remedies:

Therapy How It Works Effectiveness for Pimples Scars
Polynucleotide Injections Hydrates pores and skin, improves elasticity, makes collagen Removes broken pores and skin and makes new pores and skin
Microneedling with RF Creates small accidents to make collagen Confirmed for pimples scars
Laser Remedy (CO₂, Fraxel, PDL) It would enhance texture, however it isn’t confirmed for deep scars Very efficient for deep scars
Hyaluronic Acid (HA) Fillers Fills in scars briefly It would enhance texture, not confirmed for deep scars
Chemical Peels Removes pores and skin, makes new cells Delicate to average enchancment for floor scars

Many dermatologists use polynucleotide injections together with different remedies. When they’re used this manner, they may assist with pimples scars. However they’re not a standalone pimples scar remedy.

Last Verdict: Are Polynucleotide Injections a Good Pimples Scar Therapy?

Polynucleotide injections promise to enhance general pores and skin high quality, however no robust scientific proof proves they’re an efficient standalone remedy for pimples scars. They could assist enhance hydration, enhance pores and skin texture, and assist collagen manufacturing, which might contribute to a smoother look. Nonetheless, for deep, atrophic scars, remedies like laser remedy, microneedling, or chemical peels stay the gold commonplace.

For those who’re searching for an pimples scar remedy, polynucleotide injections or a salmon sperm facial could be a useful add-on, however they shouldn’t be your first-line possibility. At all times seek the advice of with a dermatologist or aesthetic practitioner to find out one of the best remedy plan in your pores and skin kind and scarring severity.

Would you contemplate polynucleotide injections as a part of your skincare routine? Tell us within the feedback!

References

Araco A, Araco F, Raichi M. Scientific efficacy and security of polynucleotides extremely purified expertise (PN-HPT®) and cross-linked hyaluronic acid for average to extreme nasolabial folds: A potential, randomized, exploratory research. J Cosmet Dermatol. 2023 Jan;22(1):146-155. doi: 10.1111/jocd.15064. Epub 2022 Might 26. PMID: 35531796; PMCID: PMC10084116.

Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M, Priori M, Trocchi G; As Members of The Polynucleotides HPT™ Priming Board, Collegio Italiano delle Società Scientifiche di Medicina Estetica (Italian Faculty of the Aesthetic Drugs Scientific Societies) – SIME, AGORÀ, SIES. Consensus report on the usage of PN-HPT™ (polynucleotides extremely purified expertise) in aesthetic drugs. J Cosmet Dermatol. 2021 Mar;20(3):922-928. doi: 10.1111/jocd.13679. Epub 2020 Sep 21. PMID: 32799391; PMCID: PMC7984045.

Lampridou S, Bassett S, Cavallini M, Christopoulos G. The Effectiveness of Polynucleotides in Esthetic Drugs: A Systematic Assessment. J Cosmet Dermatol. 2024 Dec 8:e16721. doi: 10.1111/jocd.16721. Epub forward of print. PMID: 39645667.

Lee D, Choi H, Yoo Ok, Park YJ, Park HJ, Oh SM, Ji GH, Rah GC, Shin DW. Evaluation of present practices and perceived effectiveness of injectable polynucleotide for enlarged facial pores amongst beauty physicians: A survey-based analysis. Pores and skin Res Technol. 2024 Sep;30(9):e13738. doi: 10.1111/srt.13738. PMID: 39233467; PMCID: PMC11375025.

Lee DK, Oh M, Kim MJ, Oh SM. Scientific results of polynucleotide with hyaluronic acid intradermal injections on facial erythema: Efficient redness remedy utilizing polynucleotides. Pores and skin Res Technol. 2024 Sep;30(9):e70034. doi: 10.1111/srt.70034. PMID: 39258788; PMCID: PMC11388635.

Lee D, Kim MJ, Park HJ, Rah GC, Choi H, Anh ST, Ji GH, Kim MS, Kim G, Shin DW, Oh SM. Present practices and perceived effectiveness of polynucleotides for remedy of facial erythema by beauty physicians. Pores and skin Res Technol. 2023 Sep;29(9):e13466. doi: 10.1111/srt.13466. PMID: 37753681; PMCID: PMC10485387.

Lee KWA, Chan KWL, Lee A, Lee CH, Wan J, Wong S, Yi KH. Polynucleotides in Aesthetic Drugs: A Assessment of Present Practices and Perceived Effectiveness. Int J Mol Sci. 2024 Jul 27;25(15):8224. doi: 10.3390/ijms25158224. PMID: 39125793; PMCID: PMC11311621.

Lim TS, Liew S, Tee XJ, Chong I, Lo FJ, Ho MJ, Ong Ok, Cavallini M. Polynucleotides HPT for Asian Pores and skin Regeneration and Rejuvenation. Clin Cosmet Investig Dermatol. 2024 Feb 13;17:417-431. doi: 10.2147/CCID.S437942. PMID: 38371328; PMCID: PMC10874187.

Park KY, Seok J, Rho NK, Kim BJ, Kim MN. Lengthy-chain polynucleotide filler for pores and skin rejuvenation: efficacy and issues in 5 sufferers. Dermatol Ther. 2016 Jan-Feb;29(1):37-40. doi: 10.1111/dth.12299. Epub 2015 Nov 2. PMID: 26814448.

Rho NK, Han KH, Cho M, Kim HS. A survey on the beauty use of injectable polynucleotide: The sample of apply amongst Korean Dermatologists. J Cosmet Dermatol. 2024 Apr;23(4):1243-1252. doi: 10.1111/jocd.16125. Epub 2023 Dec 13. PMID: 38093498.

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