Pre-Exercise Powered by enfinity® Paraxanthine

Positive aspects in Bulk NO MATTER WHAT pre-workout swaps caffeine for enfinity® paraxanthine — delivering clear power that works no matter your caffeine genetics. 300mg paraxanthine + 6g citrulline + clear dosing = afternoon exercises with out sleep points.

The pre-workout class has been dominated by the identical caffeinated formulation for years: high-stim blends that go away you jittery, crashed, and questioning whether or not that late-afternoon exercise was well worth the sleepless night time forward. Positive aspects in Bulk is altering that narrative with their revolutionary NO MATTER WHAT™ pre-workout, powered by TSI Group’s breakthrough enfinity® paraxanthine.

This is not simply one other caffeine-loaded pre-workout with a flashy label. NO MATTER WHAT™ delivers what the business has sorely wanted: clear, sustained power with out the crash, enhanced focus that does not flip into anxiousness, and efficiency advantages that work constantly throughout completely different metabolizer varieties. With 300mg of enfinity® paraxanthine main a clear, naturally-sweetened formulation, this pre-workout is designed to carry out when it issues most.

Clear Vitality That Works NO MATTER WHAT Your Caffeine Genetics

Whereas 93% of American adults devour caffeinated drinks every day, roughly 50% are thought-about gradual caffeine metabolizers who do not expertise optimum advantages from conventional caffeine consumption. That is the place enfinity® paraxanthine adjustments every thing, delivering the power and focus you need with out the genetic lottery that determines your caffeine response.

From the identical progressive group behind TSI Group’s OptiClear know-how featured in Positive aspects SHAPE, enfinity® supplies a extra refined various that works constantly throughout completely different metabolizer varieties, making NO MATTER WHAT™ the proper pre-workout for anybody who’s felt let down by conventional stimulants.

Earlier than diving into the formulation, join PricePlow’s Positive aspects in Bulk information alerts and examine present pricing under, then let’s get into the science:

NO MATTER WHAT Substances

Every serving of NO MATTER WHAT™ supplies a clear, clinically-dosed formulation designed for sustained power, enhanced focus, and superior pumps:

• L-Citrulline (Vegan Fermented) – 6000mg

  The 6g dose of L-citrulline in NO MATTER WHAT begins issues off with one of the vital efficient pump-enhancing elements. Conventional nitric oxide boosters relied on L-arginine, however citrulline supplies a extra environment friendly pathway to raise plasma arginine ranges and help enhanced blood circulation throughout coaching.

  Superior nitric oxide pathway

  Oral L-citrulline supplementation raises plasma L-arginine focus extra successfully than L-arginine itself, resulting from citrulline’s resistance to breakdown by intestinal enzymes.^[1] As soon as absorbed, citrulline converts to arginine within the kidneys by means of the citrulline-NO cycle, offering substrate for nitric oxide synthase enzymes to supply the nitric oxide that drives vasodilation and enhanced muscle blood circulation.

  Efficiency and pump advantages

  Analysis demonstrates that L-citrulline supplementation improves train efficiency by means of a number of mechanisms. Research present that citrulline can improve high-intensity train efficiency whereas bettering oxygen uptake kinetics — the velocity at which your muscle mass can make the most of oxygen in the course of the vital transition from relaxation to train.^[2] The massive 6g dose in NO MATTER WHAT aligns with analysis displaying that larger doses of citrulline (6-8g) are handiest for enhancing train capability and the muscle pumps that athletes search from their pre-workout.

  Past the rapid coaching advantages, L-citrulline might help quicker restoration between units by facilitating higher nutrient supply and waste product elimination by means of improved blood circulation to working muscle mass.^[3,4] This enhanced circulation helps preserve efficiency all through longer coaching periods whereas contributing to the satisfying muscle pump that indicators efficient coaching stimulus.

• Beta-Alanine – 3200mg

  

  Beta-alanine is likely one of the most researched endurance-boosting elements in sports activities diet, and NO MATTER WHAT delivers a full scientific dose. This non-essential amino acid does not immediately gas your muscle mass, however helps them not directly, because it acts because the rate-limiting precursor to carnosine synthesis, creating considered one of your physique’s most vital intracellular pH buffers.^[5]

  The carnosine connection

  Once you complement with beta-alanine, you are basically loading your muscle fibers with elevated carnosine concentrations. Analysis exhibits that 4 weeks of supplementation at 4-6g every day can increase muscle carnosine ranges by as much as 64%.^[5] This issues as a result of carnosine serves as your muscle mass’ inside buffer system, serving to preserve optimum pH ranges when lactic acid begins increase throughout intense train.

  Efficiency advantages the place it counts

  The 3200mg dose in NO MATTER WHAT™ hits the candy spot for efficiency enhancement. Meta-analysis analysis demonstrates that beta-alanine supplementation considerably improves train efficiency, with probably the most pronounced results occurring throughout high-intensity efforts lasting 1-4 minutes.^[6] This makes it good for these last reps, prolonged units, or any coaching that pushes you into that burn zone the place lesser pre-workouts fall brief.

  The dose right here might carry a tingling sensation (paresthesia) that some expertise with beta-alanine, however this can be a innocent and non-toxic sensation that lets customers know that it is time to get coaching. By delivering 3.2g as a part of your pre-workout routine moderately than requiring a number of every day doses, NO MATTER WHAT™ supplies comfort whereas sustaining effectiveness for constructing these carnosine shops over time.

• Alpha-GPC (Alpha-Glyceryl Phosphoryl Choline) – 300mg

  

  Alpha-GPC is a potent cognitive enhancer that works by means of growing acetylcholine ranges within the mind, making it the proper complement to enfinity® paraxanthine’s clear power profile. As a choline-containing phospholipid that may cross the blood-brain barrier, Alpha-GPC supplies the uncooked supplies for acetylcholine synthesis — the neurotransmitter accountable for focus, reminiscence, and the mind-muscle connection that drives efficiency.

  Analysis has proven that Alpha-GPC supplementation can improve cognitive efficiency in wholesome people, with a 200mg dose (much less than we’ve right here) demonstrating processing speeds that had been 18% quicker than caffeine and 11% quicker than placebo on psychological efficiency duties.^[7] The 300mg dose in NO MATTER WHAT exceeds this efficient vary, offering help for enhanced psychological readability and focus throughout coaching whereas doubtlessly supporting the neuromuscular effectivity that interprets to raised pressure manufacturing.

  What units Alpha-GPC aside from different choline sources is its superior bioavailability and its dual-action advantages. Whereas it sharpens psychological focus for higher coaching depth, it concurrently helps the acetylcholine pathways on the neuromuscular junction, which is the vital communication level between your nervous system and muscle mass. This creates a synergistic impact the place enhanced cognitive operate immediately interprets to improved bodily efficiency, making each rep extra centered and each set extra productive.^[8]

  And now for the star of the present:

• Paraxanthine (as enfinity®) – 300mg

  

  Enfinity® paraxanthine represents the evolutionary leap past conventional caffeine supplementation. Though a overwhelming majority of American adults depend on caffeine every day, roughly 50% are gradual metabolizers who expertise suboptimal advantages from customary caffeine consumption.^[9] NO MATTER WHAT’s 300mg dose of enfinity® delivers the power and focus advantages you need whereas eliminating the genetic variability that makes caffeine unreliable for a lot of customers.

  The caffeine metabolism downside

  Once you devour caffeine, roughly 84% converts to paraxanthine, with the rest forming theobromine (~12%) and theophylline (~4%).^[9] The issue lies with these latter metabolites — they’ve considerably longer half-lives: 6.2 hours for theobromine and 7.2 hours for theophylline in comparison with paraxanthine’s 3.1 hours.^[9]

  Even worse, theophylline is thought to trigger diarrhea, nausea, and irregular heartbeat — it is actually a prescription bronchodilator with poisonous doses as little as 7.5mg/kg.^[10] By taking pure paraxanthine, you sidestep the conversion to those problematic metabolites completely.

  Enhanced cognitive and bodily efficiency

  Latest analysis demonstrates that paraxanthine can the truth is ship superior advantages in comparison with caffeine. In a 2024 examine analyzing cognitive operate after a 10km run, paraxanthine supplementation improved response occasions and decreased cognitive errors extra successfully than caffeine.^[11] The examine discovered that post-exercise response occasions had been 23.2% quicker with paraxanthine in comparison with placebo and confirmed decreased perseverative errors on cognitive assessments.

  

  Paraxanthine is the first metabolite of caffeine, offering most of caffeine’s helpful results. Now you possibly can take it immediately with enfinity!

  Past cognitive advantages, paraxanthine demonstrates spectacular bodily efficiency results. Animal analysis exhibits paraxanthine supplementation elevated forelimb grip power by 17%, treadmill train efficiency by 39%, and muscle mass in key muscle teams by 14-41%.^[12]

  Distinctive mechanisms of motion

  Enfinity® paraxanthine additionally works by means of a number of pathways that caffeine can’t entry. Like caffeine, it features as an adenosine receptor antagonist, however with larger binding efficiency for each A1 and A2A receptors.^[11] Extra importantly, paraxanthine inhibits phosphodiesterase 9 (PDE9), which terminates nitric oxide neurotransmission — an impact that caffeine does not produce.^[11]

  This PDE9 inhibition potentiates nitric oxide pathways, supporting enhanced blood circulation and doubtlessly explaining why preclinical analysis exhibits paraxanthine can improve nitric oxide ranges by 100% in comparison with management.^[12] The result’s doubtlessly improved blood circulation to working muscle mass throughout train whereas supporting enhanced cognitive operate.

  Metabolic and physique composition advantages

  Latest human analysis additionally reveals that paraxanthine supplies important metabolic benefits. A dose-response examine discovered that paraxanthine elevated power expenditure by roughly 100 energy over three hours whereas concurrently lowering urge for food and starvation sensations.^[13] Not like caffeine, these results occurred with out will increase in blood strain or unfavorable cardiovascular impacts.

  

  Cleaner power profile

  The 300mg enfinity® dose in NO MATTER WHAT™ supplies sustained power with out the everyday caffeine drawbacks. Paraxanthine has much less bitterness than caffeine, making it simpler to formulate with higher style profiles. Extra importantly, its shorter half-life and quicker clearance imply you possibly can prepare later within the day with out compromising sleep high quality.

  This makes NO MATTER WHAT™ splendid for afternoon and night exercises the place conventional caffeine would intervene with restoration sleep. The constant results throughout completely different metabolizer varieties imply everybody will get the identical dependable power and focus advantages, making this really a pre-workout that works NO MATTER WHAT™ your caffeine genetics.

  For complete details about paraxanthine analysis and mechanisms, see our detailed information: Paraxanthine: Caffeine’s Main Metabolite for Laser-Focused Vitality.

• L-Theanine – 250mg

  L-Theanine supplies the proper complement to enfinity® paraxanthine, delivering calm focus with out compromising power or efficiency. This naturally occurring amino acid, discovered primarily in tea leaves, works by means of a number of mechanisms to boost the pre-workout expertise whereas mitigating potential stimulant-related negative effects.

  L-Theanine’s main mechanism entails growing gamma-aminobutyric acid (GABA) manufacturing within the mind, selling leisure and lowering stress with out sedation.^[14] The amino acid additionally modulates different key neurotransmitters together with serotonin and dopamine, contributing to improved temper and focus throughout coaching periods.

  

  The 250mg dose in NO MATTER WHAT is clinically validated and works synergistically with paraxanthine. Analysis demonstrates that L-theanine enhances the cognitive advantages of stimulants whereas lowering negative effects like jitters or anxiousness.^[15] When mixed with stimulants, L-theanine improves consideration accuracy, response time, and dealing reminiscence whereas concurrently lowering headache rankings and psychological fatigue.

  This mix creates what’s often known as “calm power” — the alertness and focus you need out of your pre-workout with out the overstimulation that may intervene with mind-muscle connection and coaching high quality. For NO MATTER WHAT customers, this interprets to sustained focus all through your complete exercise, whether or not you are hitting PRs or grinding by means of high-volume coaching periods.

• Natural Pink Himalayan Salt – 200mg

  Natural Pink Himalayan Salt supplies 78mg of sodium per serving, delivering important electrolyte help for optimum coaching efficiency. Throughout intense train, your physique loses sodium by means of sweat at charges that may considerably affect efficiency, muscle operate, and hydration standing.^[16]

  This average sodium dose helps preserve correct fluid stability with out the extreme consumption that may result in bloating or discomfort throughout coaching. Including sodium to pre-workouts helps enhanced water retention in muscle mass, improved nutrient supply, and upkeep of regular muscle contraction mechanisms that may be compromised throughout prolonged coaching periods.

  

  Not like common desk salt, Pink Himalayan salt accommodates hint minerals that complement the formulation’s pure method. At 78mg sodium (3% Each day Worth), this dose supplies significant electrolyte help with out requiring further supplementation for many coaching periods, making NO MATTER WHAT an entire pre-workout answer that addresses each power and hydration wants.

Flavors Accessible: Flavoring Powered by Sensapure Flavors!

Under is a listing of flavors the PricePlow system has seen:

Notice that this can be a 100% naturally flavored and naturally sweetened taste system developed in partnership with Sensapure Flavors. There are zero synthetic colours or dyes.

Methods to Use NO MATTER WHAT

Combine one scoop (14.7g) with 8-12 oz of chilly water 15-Half-hour earlier than your exercise. The naturally flavored and sweetened formulation mixes cleanly with out synthetic colours or dyes, offering a clean ingesting expertise that will not go away residue in your shaker.

Timing Concerns

Due to enfinity® paraxanthine’s superior half-life profile in comparison with caffeine, NO MATTER WHAT™ is good for:

• Morning exercises – Clear power with out the crash
• Afternoon coaching – No interference with night sleep, the place paraxanthine shines

Stacking with Positive aspects SHAPE

For these following complete health targets, NO MATTER WHAT™ pairs completely with Positive aspects in Bulk’s SHAPE complement. If coaching within the morning, you should use each like so:

Pre-Exercise Technique:

• Take NO MATTER WHAT 15-Half-hour earlier than coaching
• The 300mg enfinity® dose supplies sustained power and focus
• 6g L-citrulline and beta-alanine help efficiency and endurance

Publish-Exercise Restoration:

• Use SHAPE post-workout or on non-training days
• The 200mg enfinity® dose in SHAPE helps metabolism with out overstimulation
• Creatine and L-carnitine in SHAPE complement your coaching variations

Synergistic Advantages:

• Each merchandise characteristic enfinity® paraxanthine for constant power
• NO MATTER WHAT fuels your exercises; SHAPE helps restoration and physique composition
• Pure flavoring and clear labeling throughout each formulation

SHAPE can nonetheless be taken any time on relaxation days, too.

This mix supplies complete help for coaching, restoration, and physique composition targets whereas sustaining the clear power philosophy that units Positive aspects in Bulk aside.

Conclusion: Pre-Exercise Evolution Powered by Science

NO MATTER WHAT™ is a rethinking of what pre-workout supplementation needs to be. By centering the formulation round enfinity® paraxanthine as a substitute of conventional caffeine, Positive aspects in Bulk has created a product that delivers constant outcomes no matter your genetic caffeine metabolism.

The clear, naturally-sweetened formulation addresses actual issues that athletes and health fans face: power that works while you want it, focus with out anxiousness, and efficiency advantages that do not include a crash tax. With scientific doses of confirmed elements like 6g L-citrulline, 3.2g beta-alanine, and 300mg Alpha-GPC, each element serves a function in driving higher exercises.

For anybody who’s been dissatisfied by conventional pre-workouts, whether or not resulting from jitters, crashes, or just inconsistent results, NO MATTER WHAT™ presents a science-backed various that places efficiency first. Mixed with its synergistic partnership with SHAPE for complete health help, Positive aspects in Bulk is constructing an ecosystem of dietary supplements that work as laborious as you do.