Premium Collagen + Mobile Well being Complicated

Hydrolyzed Collagen Peptides (Bovine) – 8000mg

Hydrolyzed collagen peptides from bovine sources kind the spine of Rejuven8’s method, delivering a considerable 8g dose per serving (however don’t fear, we’ll hit 10 complete grams due to 2 grams of specialised marine collagen coming later). These peptides are derived from bovine disguise and endure enzymatic hydrolysis to interrupt down the collagen into smaller, extra bioavailable peptide fragments that your physique can simply soak up and make the most of.

Bovine collagen is primarily sort I and sort III collagen — probably the most ample types within the human physique that present structural assist to pores and skin, bones, tendons, and connective tissues. When ingested, these peptides can stimulate fibroblasts (the cells chargeable for collagen manufacturing) to synthesize new collagen and different extracellular matrix proteins.^[1]

Medical analysis reveals that common consumption of collagen peptides can enhance pores and skin elasticity, hydration, and dermal collagen density. A double-blind, placebo-controlled research confirmed that after simply 8 weeks of supplementation, pores and skin elasticity elevated considerably in comparison with placebo.^[1] These advantages proceed to enhance with constant use.

Past pores and skin well being, bovine collagen peptides have been clinically proven to assist joint well being and mobility. A randomized, placebo-controlled research discovered that collagen supplementation diminished joint ache in lively people and athletes.^[2] The researchers noticed important enhancements in joint ache whereas strolling, standing, and carrying objects… actions that generally trigger discomfort in people with joint points.

Research additionally counsel potential advantages for bone density, muscle restoration, and intestine well being. The wealthy glycine and proline content material helps the physique’s pure collagen synthesis whereas offering amino acids which may be underrepresented in trendy diets.

At 8g per serving, Rejuven8 supplies a clinically efficient dose of bovine collagen peptides, and that’s not even counting the extra 2g of specialised marine collagen (with CollaMeta®) that we’ll cowl shortly after discussing creatine. This mixed strategy ensures complete collagen assist in your physique’s structural and regenerative wants.

Creatine Monohydrate – 3000mg

Creatine monohydrate is a game-changing addition that elevates Rejuven8 past typical collagen dietary supplements. At a medical dose of 3000mg, this powerhouse ingredient brings spectacular mobile vitality and anti-aging advantages to the method.

Creatine isn’t only for athletes and bodybuilders. Your physique naturally produces this compound from amino acids, however supplementation can considerably enhance muscle phosphocreatine shops by 20-40%, enhancing mobile vitality manufacturing.^[3]

Why Creatine in a Collagen Product?

This sensible pairing makes good sense when you think about creatine’s whole-body advantages:

• Mobile Power Manufacturing – Creatine helps regenerate ATP (your cells’ main vitality foreign money), supporting general mobile operate and vitality.^[4]
• Pores and skin Well being Help – Analysis suggests creatine might help preserve pores and skin cell vitality metabolism and defend in opposition to oxidative injury, complementing collagen’s structural advantages for pores and skin.^[5,6]
• Cognitive Operate – Research present creatine supplementation will increase mind creatine content material by 5-15%, doubtlessly enhancing psychological vitality, focus, and cognitive efficiency – particularly throughout stress or sleep deprivation.^[7]
• Joint and Muscle Help – Past offering uncooked supplies via collagen, Rejuven8 delivers creatine to boost the vitality manufacturing wanted for tissue upkeep and restore.^[8]

For girls particularly, creatine affords distinctive advantages all through varied life phases, supporting hormone-driven adjustments in creatine metabolism.^[9]

Fluctuations in creatine kinase exercise monitor carefully with feminine hormones, revealing why creatine supplementation might supply distinctive advantages for ladies at totally different lifecycle phases.^[9]

The 3000mg dose is ideal — adequate to supply significant advantages whereas avoiding the necessity for a separate loading section that greater doses would require. This considerate dosing technique makes Rejuven8 an environment friendly all-in-one resolution for mobile vitality, tissue assist, and anti-aging.

And in contrast to many elements that lack long-term security knowledge, creatine monohydrate’s been extensively studied for many years, with analysis confirming its security profile throughout numerous populations.^[10]

By together with this research-backed ingredient at a medical dose, GR8 Life-style reveals their type, being unafraid to make a science-based formulation that goes far past superficial advantages, and goes barely in opposition to the norm, too — and in a good way!

Hydrolyzed Marine Collagen (with CollaMeta®) – 2000mg

Whereas bovine collagen supplies wonderful baseline assist, GR8 Life-style takes collagen supplementation to the subsequent degree by together with 2g of premium marine collagen that includes CollaMeta – a complicated marine collagen tripeptide from Glanbia Nutritionals.

Six-month research outcomes present important enhancements in LDL/HDL ratios, significantly in high-risk people with ratios above 2.5, demonstrating cardiovascular advantages past pores and skin well being.^[11]

What makes CollaMeta particular? It’s a extremely potent collagen tripeptide with a small molecular weight, making it considerably extra bioavailable than conventional collagen peptides. This implies you want much less for a similar impact – a real instance of high quality over amount.

Meet Bioactive Tripeptides

CollaMeta comprises the next proportion of bioactive tripeptides (particularly these with Gly-X-Y sequences) that assist the synthesis of assorted forms of collagen all through your physique. Probably the most frequent of those tripeptide models is Glycine-Proline-Hydroxyproline (Gly-Professional-Hyp), which contributes most stability to collagen’s triple-helix construction whereas exhibiting potent bioactivity.^[12]

Medical knowledge reveals significant reductions in poisonous superior glycation end-products (TAGE) after 6 months, particularly in topics with elevated baseline ranges, supporting collagen’s whole-body advantages.^[11]

These collagen tripeptides don’t simply move via your system — medical analysis reveals they’re effectively absorbed into the bloodstream. After oral ingestion, tripeptides like Gly-Professional-Hyp are detected in human plasma, with concentrations peaking round 30-60 minutes post-consumption.^[13]

The advantages of CollaMeta lengthen to a number of areas:

• Superior pores and skin hydration and elasticity – A 12-week medical research demonstrated important enhancements in pores and skin hydration and elasticity in comparison with placebo.^[14]
• Cardiovascular well being assist – A 6-month research discovered collagen tripeptide supplementation considerably diminished the LDL-C/HDL-C ratio in people with greater preliminary ratios and lowered poisonous superior glycation end-products (TAGE) in all topics.^[11]
• Potential joint and bone advantages – Analysis suggests collagen tripeptides might present helpful results on bone therapeutic processes and joint well being.^[15]

By combining each marine and bovine collagen sources, Rejuven8 supplies a complete spectrum of collagen sorts to assist general connective tissue well being all through your physique.

Maca (Lepidium meyenii Walp) (Root) Powder – 1000mg

Native to the high-altitude areas of the Peruvian Andes, maca root has been cultivated for over 2,000 years as each a meals supply and conventional medication.^[16] This adaptogenic powerhouse brings a number of advantages to Rejuven8’s method past what you’d sometimes count on in a collagen complement.

Maca comprises distinctive bioactive compounds together with macamides, macaenes, glucosinolates, and flavonoids that contribute to its spectacular array of advantages.^[17] Analysis reveals maca might help:

• Increase Power & Fight Fatigue

  Maca supplementation has demonstrated important anti-fatigue results, serving to to increase train length whereas lowering muscle injury from oxidative stress.^[18] In a single research, athletes who consumed 1500mg of maca every day for 60 days confirmed a mean 10.3% enchancment in bodily efficiency.^[16]

• Help Antioxidant Protection

  Maca’s potent antioxidant properties come from its polyphenols and distinctive alkaloids, which assist neutralize free radicals and cut back oxidative injury.^[19] These results complement Rejuven8’s anti-aging focus by supporting mobile well being from a number of angles.

• Improve Temper & Cognitive Operate

  Analysis suggests maca supplies neuroprotective advantages via its antioxidant and anti inflammatory actions.^[16] Maca seems to modulate neurotransmitter exercise and will assist enhance reminiscence and cognitive efficiency.

• Enhance Train Restoration

  A randomized, placebo-controlled research discovered that cyclists supplementing with maca extract confirmed considerably improved 40km time trial efficiency after simply 14 days.^[20] This makes maca a sensible addition to a method designed to assist lively life.

At 1000mg per serving, Rejuven8 delivers a research-backed dose of maca that works synergistically with different elements to assist mobile well being, vitality manufacturing, and general wellness—really elevating this method past typical collagen dietary supplements.

Turmeric (Curcuma longa) (Rhizome) Extract (as Curcumin C3 Complicated®) – 300mg

Curcumin C3 Complicated is a premium, patented extract derived from the rhizomes of turmeric (Curcuma longa), standardized to comprise a minimal of 95% curcuminoids.^[21] This potent mix options three bioactive compounds in particular ratios: curcumin (70-80%), demethoxycurcumin (15-25%), and bisdemethoxycurcumin (2.5-6.5%).^[22]

Complete Pores and skin Advantages

Curcumin isn’t shocking to see in Rejuven8 — it has a formidable vary of constructive results, together with pores and skin well being advantages. Curcumin works via a number of pathways to assist pores and skin rejuvenation and safety:

• Enhanced Collagen Synthesis – Curcumin doesn’t simply assist current collagen, it really helps stimulate new collagen manufacturing. Analysis reveals curcumin helps fibroblasts (the cells chargeable for collagen synthesis) and may enhance each collagen and hyaluronan manufacturing, instantly complementing Rejuven8’s collagen peptides.^[23]
• Pores and skin Barrier Help – Medical research display that curcumin helps preserve and strengthen the pores and skin barrier operate, which tends to weaken with age. This impact helps pores and skin retain moisture and resist environmental stressors.^[24]
• Photograph-Ageing Safety – Research present curcumin helps defend pores and skin cells from UV injury by inhibiting the manufacturing of skin-damaging inflammatory cytokines, lowering the creation of reactive oxygen species, and selling pores and skin cell survival after UV publicity.^[25]
• Pores and skin Hydration Enhancement – A randomized, double-blind, placebo-controlled trial demonstrated that oral curcumin supplementation considerably elevated pores and skin hydration by stimulating hyaluronan manufacturing from non-stimulated keratinocytes, offering a pure moisturizing impact.^[25]

Anti-Inflammatory Help

Past pores and skin advantages, Curcumin C3 Complicated itself delivers highly effective anti-inflammatory properties that assist whole-body wellness. It really works by inhibiting NF-κB activation, which reduces the manufacturing of inflammatory cytokines and enzymes like cyclooxygenase-2 (COX-2).^[23] This mechanism is particularly helpful for supporting pores and skin therapeutic, joint consolation, and restoration after train.

Analysis confirms that curcumin can successfully modulate inflammatory responses in a number of pores and skin situations, making it a flexible ingredient for complete pores and skin well being assist.^[24]

Potent Antioxidant Safety

Oxidative stress accelerates pores and skin ageing and mobile injury all through the physique. Curcumin C3 Complicated delivers spectacular antioxidant advantages via a dual-action strategy:

• It instantly neutralizes dangerous free radicals that injury pores and skin cells and collagen fibers
• It boosts your physique’s personal antioxidant protection techniques by activating Nrf2, the grasp regulator of mobile antioxidant responses^[23]

This complete antioxidant assist helps defend pores and skin cells from oxidative injury whereas supporting general mobile well being and longevity.

Wound Therapeutic Help

For lively people, curcumin supplies priceless assist for pores and skin restoration and therapeutic. Research present curcumin enhances wound therapeutic by:^[23]

• Selling sooner re-epithelialization
• Rising collagen deposition at wound websites
• Supporting wholesome tissue granulation
• Decreasing oxidative injury throughout the therapeutic course of[

These benefits make curcumin an excellent complement to Rejuven8’s regenerative formula, supporting not just daily skin maintenance but also active recovery.

Cardiovascular and Cognitive Support

Clinical research also shows that the curcuminoids in C3 Complex can significantly reduce LDL cholesterol, total cholesterol, and triglycerides while increasing beneficial HDL cholesterol.[https://pubmed.ncbi.nlm.nih.gov/25440375/]

Moreover, latest research counsel curcumin might assist mind well being and cognitive operate, significantly working reminiscence.^[27] This aligns with GR8’s complete strategy to wellness that addresses each bodily and psychological features of wholesome ageing.

The 300mg dose in Rejuven8 supplies significant advantages whereas sustaining wonderful tolerability and security. By together with this clinically-researched ingredient, GR8 Life-style ensures that Rejuven8 delivers complete assist for pores and skin well being, mobile operate, and general vitality that actually transcends primary collagen dietary supplements.

Coenzyme Q10 – 100mg

Coenzyme Q10 (CoQ10) is a robust, vitamin-like compound that your physique naturally produces, however ranges decline with age and bodily stress. At 100mg per serving, Rejuven8 delivers a medical dose of this important nutrient that works on the mobile degree to assist a number of features of well being and efficiency.

CoQ10 performs a vital function in your mitochondria, the place it helps convert meals into ATP vitality via the electron transport chain.^[28] This makes it particularly priceless for high-energy demanding tissues like your coronary heart, kidneys, liver, and muscular tissues.

Past its bioenergetic operate, CoQ10 acts as considered one of your physique’s main fat-soluble antioxidants, defending cell membranes from oxidative injury. It’s the one lipid-soluble antioxidant that your physique synthesizes endogenously and has enzymatic mechanisms to regenerate its diminished kind, making it uniquely priceless for mobile safety.^[29]

Analysis reveals that CoQ10 supplementation can considerably cut back oxidative stress markers and enhance complete antioxidant capability.^[30] For athletes or lively people, CoQ10 might assist cut back exercise-induced muscle injury and enhance restoration.^[31]

As an additional advantage, CoQ10 helps preserve wholesome cardiovascular operate by supporting correct blood strain ranges and endothelial well being.^[32]

Via these a number of mechanisms, the CoQ10 in Rejuven8 works synergistically with different elements to assist mobile rejuvenation, vitality manufacturing, and general vitality.

Vitamin C (as Acerola Cherry Extract) – 135mg

Rejuven8 doesn’t use artificial ascorbic acid – it delivers 135mg of vitamin C (150% DV) from acerola cherry extract, considered one of nature’s richest sources of this important nutrient. An excellent-tasting supply, too!

Acerola comprises 50-100 instances extra vitamin C than oranges or lemons, with concentrations starting from 1,500-4,500mg per 100g of fruit.^[33] Research counsel that vitamin C from pure meals matrices like acerola could also be higher absorbed by the physique than artificial types.^[34]

However why embody vitamin C in a collagen method? The reply is easy – it’s important for collagen synthesis. Vitamin C serves as a cofactor for the enzymes prolyl and lysyl hydroxylase, which stabilize the collagen molecule’s construction.^[35] With out sufficient vitamin C, collagen manufacturing turns into compromised, resulting in potential pores and skin fragility and impaired wound therapeutic.

Past its collagen-supporting function, vitamin C capabilities as a robust antioxidant that protects in opposition to oxidative stress, which might degrade current collagen.^[36] It neutralizes free radicals and regenerates different antioxidants like vitamin E, making a synergistic impact with the pine bark extract and CoQ10 additionally present in Rejuven8.

The advantages lengthen additional – vitamin C enhances immune operate, helps cardiovascular well being, and will even enhance your physique’s response to train.^[37]

For optimum collagen assist, vitamin C works synergistically with the marine and bovine collagen peptides in Rejuven8, making it a vital part of this complete mobile well being method.

Pine (Pinus pinaster) (Bark) Extract (95% Proanthocyanidins) – 50mg

Pine bark extract from the French maritime pine (Pinus pinaster) provides highly effective vascular and pores and skin assist advantages to Rejuven8’s method. This concentrated supply of proanthocyanidins (specialised polyphenols with robust antioxidant capabilities) works synergistically with collagen to boost pores and skin elasticity and mobile wellness.

Highly effective Antioxidant Safety

Pine bark extract comprises a novel mix of procyanidins, bioflavonoids, and phenolic acids that neutralize free radicals extra successfully than many different antioxidants. Analysis reveals it may possibly lengthen the lifetime of vitamin C and regenerate vitamin E, making a complete antioxidant community that protects collagen fibers from degradation.^[38]

Enhanced Pores and skin Elasticity & Look

Useful in Rejuven8 is pine bark’s skill to strengthen current collagen whereas selling new collagen synthesis. A medical research discovered that supplementation with pine bark extract considerably elevated pores and skin elasticity and diminished wrinkle depth by upregulating genes related to hyaluronic acid and collagen manufacturing.^[39]

Improved Circulation & Nutrient Supply

Pine bark extract helps wholesome blood circulate by enhancing endothelial nitric oxide manufacturing, which helps blood vessels dilate correctly.^[40] This improved microcirculation means higher supply of oxygen and vitamins to pores and skin cells, supporting their pure regeneration processes.

Anti-Inflammatory Help

The proanthocyanidins in pine bark extract assist modulate the physique’s inflammatory response by inhibiting NF-κB activation and lowering inflammatory enzyme manufacturing.^[41] This anti-inflammatory motion enhances Rejuven8’s curcumin to supply complete assist for pores and skin well being and restoration.

At 50mg per serving standardized to 95% proanthocyanidins, Rejuven8 delivers a research-backed dose of this premium ingredient to assist pores and skin vitality, vascular well being, and mobile safety from inside.