

Cistamax from Nootropics Depot combines three cistanche extracts with PrimaVie shilajit, pregnenolone, and DHEA for complete testosterone help. Get 85mg echinacoside per serving plus hormone precursors in a single handy method. Extra bioactives, higher worth than shopping for individually.
Cistanche tubulosa has earned its legendary standing as “desert ginseng” by way of centuries of conventional use and preliminary trendy scientific analysis. From reportedly sustaining Genghis Khan’s military by way of harsh desert crossings to supporting pure testosterone manufacturing in right this moment’s analysis, this exceptional herb continues to ship highly effective advantages for male vitality and general wellness.
Cistamax: Elite-Tier Cistanche Pure Testosterone Booster from Nootropics Depot
Whereas particular person cistanche dietary supplements supply spectacular advantages, Nootropics Depot Cistamax takes issues to the following stage by combining a complete cistanche advanced with a couple of rigorously chosen synergistic components. This superior method contains three totally different types of cistanche alongside PrimaVie shilajit with two essential hormone precursors in micronized pregnenolone and DHEA to create an entire testosterone and vitality help system.
This text focuses on the components in Cistamax, however for the full story behind cistanche’s fascinating historical past and mechanisms, you should definitely take a look at our Final Information to Cistanche Dietary supplements, which explores every little thing from conventional makes use of to the newest analysis to cutting-edge extraction strategies. Right here, we’ll key in on how Cistamax optimizes this historical knowledge with trendy dietary science.
Able to expertise the ability of this superior cistanche stack? Take a look at present pricing and join PricePlow’s Nootropics Depot alerts under:
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Cistamax Elements
Every capsule of Cistamax supplies a complete mix of compounds that will help wholesome testosterone ranges, all designed to work synergistically for max effectiveness:
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Cistamax Optimized Cistanche Advanced – 500mg
The guts of this method incorporates a brilliantly-designed cistanche advanced that captures the full spectrum of this exceptional herb’s bioactive compounds. This 500mg mix contains:
- 300mg Entire Cistanche Powder (Cistanche tubulosa stem) offering the entire plant matrix with pure ratios of phenylethanoid glycosides, polysaccharides, and supporting compounds
- 100mg Supercritical CO2 Extract (Cistanche tubulosa stem) using cutting-edge extraction expertise to protect unstable fragrant compounds usually misplaced in conventional processing
- 100mg Water/Ethanol Extract (Cistanche tubulosa stem) delivering concentrated bioactive compounds by way of time-tested extraction strategies
This triple extract method ensures you obtain 85mg echinacoside and 33mg acetoside/verbascoside per serving, offering each the compounds and the mood-enhancing constituents that make cistanche distinctive and will assist help pure testosterone manufacturing. The mix of full-spectrum powder, concentrated extracts, and preserved unstable compounds creates an entourage impact that captures each conventional advantages and trendy optimization.
However what is cistanche?
Cistanche Tubulosa: The “Desert Ginseng” with Legendary Standing
Deep within the harsh deserts of China and Mongolia grows one in every of nature’s most exceptional adaptogenic crops: Cistanche tubulosa, affectionately referred to as “desert ginseng”, is an enchanting plant that fully lacks chlorophyll and survives by absorbing vitamins from different crops in a few of Earth’s most unforgiving environments.[1] This extraordinary survival technique has allowed it to pay attention distinctive bioactive compounds that merely can’t be discovered elsewhere in nature.
Cistanche tubulosa, the “desert ginseng” that saved Genghis Khan’s military, naturally helps testosterone by way of enhanced enzyme manufacturing. Fashionable analysis validates 2,000+ years of use for hormonal well being, cognitive perform & vitality.
For over two millennia, Cistanche has held legendary standing in Conventional Chinese language Medication, the place it was labeled as a “first-class” tonic and revered as one of many “9 Most important Chinese language Herbs”. Historical texts doc its use for supporting vitality, enhancing reproductive well being, strengthening immunity, and sharpening psychological readability. Maybe most famously, Cistanche reportedly sustained Genghis Khan’s military throughout their brutal desert crossings, incomes it a spot in army historical past in addition to natural medication.
Fashionable Science Validates Historical Knowledge
Fashionable analysis has lastly begun to uncover the mechanisms behind the plant’s unimaginable results. The first bioactive compounds chargeable for Cistanche’s advantages are echinacoside and acetoside (additionally referred to as verbascoside) – two molecules that work by way of a number of complementary pathways to help each hormonal stability and cognitive perform.[2]
- Testosterone Help Via A number of Mechanisms: Cistanche enhances pure testosterone manufacturing by upregulating your entire steroidogenic enzyme cascade, together with CYP11A1, 3β-HSD, CYP17A1, and 17β-HSD – basically optimizing each step of the physique’s testosterone synthesis equipment.[2] Moreover, it boosts luteinizing hormone (LH) ranges, which sign the testes to extend testosterone manufacturing. In managed animal analysis inspecting endocrine disruption, Cistanche demonstrated the flexibility to revive testosterone ranges by as much as 77% after BPA-induced suppression.
- Distinctive Progress Hormone Activation: Additionally fascinating is Cistanche’s means to activate ghrelin receptors, triggering progress hormone secretion by way of a mechanism not often seen in nature.[1] Echinacoside exhibits the strongest binding affinity to those “starvation receptors”, but apparently does not all the time produce classical urge for food results, making it a singular “non-peptidyl ghrelin analog” with anti-aging potential.
Highly effective Nootropic Functions
Past its famend testosterone advantages, Cistanche demonstrates exceptional cognitive-enhancing properties that make it a respectable nootropic compound:
- Mind-Derived Neurotrophic Issue (BDNF) Restoration: Echinacoside demonstrates an unimaginable means to revive BDNF ranges again to regular by way of tyrosine kinase receptor stimulation.[3] BDNF is likely one of the mind’s most important progress components, supporting neuronal survival, selling new synapse formation, and enhancing the mind’s capability for studying and reminiscence formation.
- Nerve Progress Issue (NGF) Enhancement: Cistanche additionally enhances nerve progress issue manufacturing, resulting in measurable enhancements in neuronal perform and construction.[4] Research present it will increase neuronal cell differentiation, promotes neurite size extension, and enhances synapse formation within the hippocampus, correlating with practically 2-fold enhancements in retention time throughout cognitive exams in animals.
- Scientific Cognitive Advantages: A current 90-day randomized, double-blind, placebo-controlled trial demonstrated vital cognitive enhancements in middle-aged and aged members.[5] Members confirmed enhancements in Mini-Psychological State Examination scores, Montreal Cognitive Evaluation scores, and World Well being Group High quality of Life scores, demonstrating Cistanche’s real-world cognitive advantages. Word that this examine included one other ingredient not on this complement (ginkgo biloba), however it’s promising nonetheless!
All the higher is the triple extract that Nootropics Depot used right here, each offering totally different bioactives from cistanche. Every may be purchased individually, however Cistamax has them all.
For these excited about diving deeper into Cistanche’s fascinating historical past, mechanisms, and purposes, you should definitely take a look at our huge Final Information to Cistanche Dietary supplements, which explores every little thing from Genghis Khan’s legendary use to right this moment’s superior standardization strategies
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PrimaVie Purified Shilajit – 150mg
PrimaVie is taken into account the gold commonplace in shilajit supplementation, delivering a purified and standardized extract of this historical Ayurvedic powerhouse. This patented kind incorporates concentrated fulvic acid complexes, dibenzo-α-pyrones (DBPs), and over 40 important hint minerals that work synergistically with cistanche’s testosterone-enhancing mechanisms.
The Science Behind Shilajit’s Efficiency Advantages
Shilajit’s exceptional results stem from its distinctive means to reinforce mitochondrial perform on the mobile stage. Analysis demonstrates that PrimaVie shilajit considerably improves post-exercise ATP focus and adenylate vitality cost — vital markers of mobile vitality standing.[6] In managed research, topics receiving PrimaVie confirmed practically double the post-exercise ATP ranges in comparison with placebo teams, translating to enhanced vitality manufacturing and decreased fatigue throughout demanding bodily actions.
The mechanism facilities on shilajit’s potent electron switch capability and mobile help exercise, which optimizes mitochondrial respiration and ATP resynthesis.[7] This enhanced mitochondrial effectivity helps clarify why 500mg each day PrimaVie supplementation for 8 weeks improved resistance to fatigue in strength-trained people, with the best advantages noticed in these with increased baseline energy ranges.
Testosterone and Hormonal Help
Past its energy-enhancing properties, PrimaVie supplies direct testosterone help by way of a number of pathways. A landmark 90-day randomized managed trial in wholesome males aged 45-55 discovered that 500mg each day PrimaVie supplementation produced spectacular hormonal enhancements: testosterone elevated by 20.45%, free testosterone by 19.14%, and DHEA-S by 31.35%.[8] These results had been accompanied by maintained luteinizing hormone (LH) ranges and elevated follicle-stimulating hormone (FSH), indicating correct hypothalamic-pituitary-testicular axis perform.
The testosterone-boosting results probably end result from shilajit’s function as a precursor supporter — offering the uncooked supplies and cofactors wanted for optimum steroid hormone synthesis. This makes it a perfect complement to cistanche’s steroidogenic enzyme enhancement, making a complete method to pure testosterone-balancing help.
At 150mg per serving, Cistamax supplies a related dose of this premium shilajit extract. Whereas the landmark testosterone research used 500mg each day, the 150mg dose in Cistamax works synergistically with the excellent cistanche advanced and hormone precursors under (pregnenolone and DHEA) that will assist help a number of facets of male vitality. This strategic dosing ensures optimum bioavailability and absorption whereas avoiding potential overstimulation of hormone pathways.
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Micronized Pregnenolone – 2.5mg
The proof is within the testing! Cistanche supplementation considerably improved scores on a number of cognitive assessments together with MMSE and MoCA exams. These aren’t simply lab outcomes – they signify actual enhancements in pondering and reminiscence.[5]
Pregnenolone serves because the “mom hormone” – the foundational constructing block from which all steroid hormones are synthesized.[9] This micronized kind ensures optimum absorption and bioavailability. By offering this important precursor, Cistamax helps your physique’s pure hormone manufacturing cascade whereas working synergistically with cistanche’s steroidogenic enzyme enhancement.
The Basis of Hormone Manufacturing
Pregnenolone stands as the primary steroid hormone synthesized from ldl cholesterol in any respect websites of steroidogenesis, together with the mind, adrenal glands, and gonads.[9] Usually referred to as the “mom of all hormones,” pregnenolone serves because the important precursor for just about all downstream steroid hormones, together with progesterone, DHEA, testosterone, estradiol, and cortisol.[10]
The biosynthesis pathway begins when ldl cholesterol enters the mitochondria of steroidogenic cells, the place the enzyme CYP11A1 converts it to pregnenolone – the rate-limiting step for all subsequent steroid hormone manufacturing.[9] This makes pregnenolone availability essential for sustaining optimum hormone stability all through the physique.
Past Hormone Precursor Features
Whereas pregnenolone’s function as a hormone precursor is well-established, analysis reveals it additionally exerts direct physiological results impartial of its conversion to different hormones.[11] These direct actions embrace neuroprotective results, cognitive enhancement, and modulation of neurotransmitter techniques.
- Neuroprotective Advantages: Pregnenolone has strong neuroprotective properties, together with safety towards amyloid-beta neurotoxicity in hippocampal cells.[10] It additionally helps nerve progress and myelination processes (the insulation of nerve fibers for quicker sign transmission), with analysis displaying pregnenolone manufacturing by is vital for correct myelination in each central and peripheral nervous techniques.[11]
- Cognitive Enhancement: Animal research exhibit pregnenolone’s means to reinforce reminiscence and cognitive perform by way of a number of mechanisms, together with modulation of GABA and NMDA receptors.[11] Analysis exhibits pregnenolone sulfate will increase acetylcholine launch and spatial recognition within the hippocampus, with results lasting a number of hours after administration.[12]
The herb supercharges your mind’s pure protection techniques! Echinacoside remedy elevated protecting enzymes in each the cortex and hippocampus whereas decreasing inflammatory markers – a one-two punch for mind well being.[3]
Synergistic Hormone Help Technique
Cistamax supplies 2.5mg of micronized pregnenolone, a rigorously chosen dose that will assist help hormone manufacturing with out overwhelming pure regulatory techniques.[11] This average dosing method acknowledges that pregnenolone supplementation works finest inside particular therapeutic home windows, the place it could improve pure steroidogenesis with out disrupting hormonal stability.
Provided that oral pregnenolone usually has restricted bioavailability and speedy metabolism, the micronized model is helpful to create smaller particle sizes in an effort to enhance absorption and utilization.[11]
When mixed with cistanche’s steroidogenic enzyme upregulation and DHEA’s direct hormone help, this pregnenolone dose creates a complete method to hormone optimization that helps the physique’s pure testosterone manufacturing equipment slightly than bypassing it.
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DHEA (Dehydroepiandrosterone) – 2.5mg
DHEA acts as one other vital hormone precursor that may be transformed to testosterone and different very important hormones as wanted by the physique. As with pregnenolone, the cautious 2.5mg dose supplies light help with out overwhelming pure hormone stability. DHEA ranges naturally decline with age, making this inclusion worthwhile for sustaining youthful hormone profiles alongside cistanche’s enzymatic help.
One other “Mom of All Hormones”
Dehydroepiandrosterone (DHEA) serves as one of the crucial ample circulating steroid hormones within the human physique and capabilities as a vital precursor to each testosterone and estradiol.[13] Usually referred to as the “mom of all hormones,” DHEA is produced primarily by the adrenal glands and peaks round age 20-25 earlier than starting a gradual decline that continues all through life.[14]
By age 75, DHEA ranges drop roughly 80% in comparison with their peak, correlating with declines in vitality, muscle mass, bone density, and general vitality. This age-related decline has made DHEA supplementation an essential technique for supporting wholesome hormone stability in getting old adults.
Direct and Oblique Hormonal Advantages
Additionally much like pregnenolone: Whereas DHEA capabilities as a testosterone precursor, current analysis reveals it additionally exerts direct physiological results impartial of its conversion to different hormones.[13] Meta-analysis analysis demonstrates that DHEA supplementation can considerably improve testosterone ranges in each women and men, with results being extra pronounced in people over 60 years of age.[14]
Past testosterone conversion, DHEA binds to particular membrane receptors and prompts a number of biochemical pathways like signaling cascades that affect mobile metabolism and performance.[14]
Complete Physiological Help
DHEA supplementation is related to quite a few advantages, together with improved endothelial perform, enhanced mobile immunity, decreased inflammatory processes, elevated bone density, improved bodily energy, and higher general physique composition.[13]
Neuroprotective and Cognitive Advantages: Lastly, DHEA use additionally has vital neuroprotective properties, together with stimulation of nerve progress issue manufacturing and safety towards neuronal harm from metabolic deprivation.[13] Latest research present DHEA can stimulate human neural stem cells, suggesting roles in neurogenesis and neuronal survival that will contribute to cognitive well being and temper regulation.
Optimum Dosing Technique
When mixed with cistanche’s steroidogenic enzyme enhancement and pregnenolone’s foundational hormone help, this 2.5mg DHEA dose creates a synergistic method to hormone optimization that helps the physique’s pure testosterone manufacturing cascade with out going overboard..
The way to Use Cistamax
Dosage: Take one capsule each day, ideally within the morning to align with pure testosterone rhythms. Cistamax may be taken with or with out meals, although some customers favor taking it with breakfast for enhanced absorption of the fat-soluble compounds.
Length: Cistamax is designed for long-term each day use. The pure mechanisms concerned – enzyme upregulation and hormone precursor help – work finest with constant supplementation slightly than biking protocols.
As mentioned in our important Cistanche information, happening 8-12 weeks of each day use after which taking a month off to evaluate off-cycle standing is a sensible concept.


Tongkat Ali analysis exhibits spectacular outcomes for testosterone help, sexual well being, stress discount, and athletic efficiency. This complete information covers the science, correct dosing, and the way to decide on high quality standardized extracts like Nootropics Depot’s lab-tested choices.
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Stacking with Tongkat Ali
For customers looking for most testosterone help, Cistamax pairs exceptionally properly with tongkat ali. These herbs work by way of complementary mechanisms – cistanche optimizes the testosterone synthesis equipment whereas tongkat ali enhances luteinizing hormone sensitivity and supplies further aromatase inhibition.
Nootropics Depot affords each 2% and 10% eurycomanone standardized tongkat ali extracts that stack completely with Cistamax. The mix creates a well-rounded method to pure testosterone optimization that addresses a number of pathways concurrently. For detailed info on tongkat ali’s mechanisms and advantages, take a look at our full information: Tongkat Ali (Eurycoma Longifolia): The Final Information to Get Your Longjack Again.
Really useful Stacking Protocol:
- Take Cistamax as soon as each day within the morning
- Add tongkat ali (200mg of two% extract or 100mg of 10% extract) both each day for max results or as wanted for added confidence and vitality help
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Physique Composition Stack with Ecklonia Cava
For these excited about complete physique composition help, Cistamax creates an progressive stack when mixed with Ecklonia cava. Whereas Cistamax optimizes testosterone and hormone stability, Ecklonia cava supplies distinctive metabolic advantages together with glucose regulation, fats browning, and urge for food optimization.
This mix addresses physique composition from a number of angles – hormonal optimization by way of Cistamax and metabolic enhancement by way of Ecklonia cava’s dieckol content material. The result’s a complete method to vitality that helps each muscle constructing and fats metabolism.
Nootropics Depot spent 6 YEARS creating their Ecklonia Cava complement, discovering most market merchandise aren’t real! Their genuine marine extract affords metabolic, cognitive and sleep advantages backed by actual science. The one verified Ecklonia Cava you may belief.
Analysis exhibits Ecklonia cava can promote the conversion of white adipose tissue to metabolically energetic brown-like fats whereas supporting wholesome glucose metabolism. Mixed with Cistamax’s testosterone and vitality help, this creates a robust synergy for general physique composition objectives.
For full particulars on Ecklonia cava’s exceptional advantages, discover our in-depth protection: Ecklonia Cava: The Tremendous Seaweed with Metabolism and Mind-Boosting Advantages and Nootropics Depot Ecklonia Cava: The 6-Yr Quest for a Superior Seaweed Supply.
Physique Composition Stack Protocol:
- Take Cistamax as soon as each day within the morning
- Add Ecklonia cava (250-500mg) to help metabolic optimization and wholesome physique composition
- Contemplate timing Ecklonia cava with meals for enhanced glucose regulation advantages
High quality Assurance: Belief Via Transparency
Nootropics Depot’s dedication to high quality extends far past spectacular formulations. Each batch of Cistamax undergoes rigorous third-party testing by way of ISO-accredited laboratories to confirm efficiency, purity, and security. Their ultra-intense testing protocol contains id verification for every botanical ingredient, quantitative evaluation of key bioactive compounds like echinacoside and verbascoside, heavy metals screening, microbial testing, and pesticide residue evaluation.
In contrast to many complement firms that rely solely on provider certificates, Nootropics Depot conducts impartial verification testing on each incoming uncooked materials and completed product batch. Their “Belief Via Transparency” philosophy means full Certificates of Evaluation (COAs) are available on their web site for each Cistamax lot quantity, permitting clients to confirm the precise efficiency and purity of their particular bottle.
This stage of transparency, mixed with cGMP-certified manufacturing in FDA-registered amenities, ensures that Cistamax persistently delivers the therapeutic advantages this exceptional formulation guarantees.
Different Nootropics Depot Cistanche Choices
In case you don’t need the shilajit and hormone precursors and simply need to attempt cistanche by itself, Nootropics Depot affords three standalone cistanche merchandise to satisfy totally different wants and budgets:
- Full Spectrum Cistanche Capsules (5% Echinacoside, 1% Acetoside) – Essentially the most economical possibility that preserves the entire plant matrix with pure ratios of all bioactive compounds, out there in handy 700mg capsules.
- Cistanche Extremely Potent Extract Tablets and Powder (50% Echinacoside, 10% Verbascoside) – The gold commonplace for conventional cistanche extracts, delivering most echinacoside content material in exact 200mg tablets or powder for constant testosterone and cognitive help.
- Supercritical CO2 Cistanche Extract (20% Echinacoside, 20% Verbascoside) – The premium “grand cru” possibility that preserves unstable compounds by way of cutting-edge extraction expertise, creating extra pronounced temper and libido results at 200mg per capsule.
Premium Worth: Extra Bioactives, Extra Elements, Much less Price
When researching testosterone help dietary supplements, evaluating particular person ingredient prices exhibits why Cistamax supplies unimaginable worth for superior customers. It isn’t simply concerning the mixture of components, however the quantity of cistanche bioactives you get in comparison with competing “pure” cistanche dietary supplements.
Superior Bioactive Content material Per Greenback
The method supplies 86.3mg of echinacoside per serving at simply 1.16 cents per milligram of energetic compound (as of 2025 pricing). This positions Cistamax because the second-highest echinacoside supply available in the market — second solely to the different Nootropics Depot choices — whereas nonetheless providing further advantages within the added components!


Nootropics Depot’s Supercritical CO2 Extract delivers 53.1mg at simply 1.4 cents per milligram, offering 13x extra verbascoside than opponents whereas costing 6x much less per mg of energetic compound.
For verbascoside content material, Cistamax delivers 39.9mg per serving at 2.5 cents per milligram (mid-2025 pricing), offering 2.4x extra verbascoside than most conventional cistanche merchandise. Cistamax customers obtain practically 10x extra energetic compounds for lower than one-third the price per milligram in comparison with the competitors!


Worth evaluation reveals Nootropics Depot’s Extremely Potent Extract leads with 110.5mg echinacoside at simply 45 cents per milligram – that is 2.2x extra energetic compound than opponents whereas sustaining the bottom price per mg.
Then there’s the worth you get from the opposite components:
Stack Alternative Worth
Cistamax’s true worth seems even higher when contemplating the person parts:
- Premium cistanche extract: $35-50 month-to-month
- PrimaVie shilajit: $25-35 month-to-month
- Micronized pregnenolone: $15-25 month-to-month
- DHEA: $10-15 month-to-month
This creates a complete month-to-month price of $85-125 for equal components from separate merchandise, whereas Cistamax supplies the entire stack in a single, handy method at a considerably decrease price level.
The one method to get extra echinacoside and verbascoside per greenback is to go along with the different Nootropics Depot merchandise listed above. However as we have lined on this article, Cistamax affords far more.
Conclusion: Cistamax is the Evolution of Cistanche Supplementation
Cistamax is a good instance of how conventional botanical knowledge may be enhanced by way of trendy dietary science. By combining three totally different types of cistanche with well-selected hormone precursors and adaptogenic compounds, this method addresses testosterone help from a number of complementary angles.


Brown seaweed Ecklonia cava outperforms land-based crops with its highly effective phlorotannins! Analysis exhibits advantages for metabolism, cognition, liver well being, and even hair progress.
The inclusion of complete plant powder preserves conventional advantages, whereas concentrated extracts and supercritical CO2 processing guarantee most bioactive supply. The addition of PrimaVie shilajit, pregnenolone, and DHEA creates an entire hormone help system that works synergistically with cistanche’s pure mechanisms.
Whether or not you are looking for to optimize testosterone ranges, improve bodily efficiency, or help general vitality, Cistamax supplies a complete method that honors cistanche’s historical legacy whereas leveraging trendy extraction and formulation strategies.
For the entire story behind cistanche’s exceptional journey from endangered desert plant to cutting-edge complement, do not miss our Final Information to Cistanche Dietary supplements. This complete useful resource explores every little thing from Genghis Khan’s legendary use to right this moment’s superior standardization strategies.
Able to expertise the following evolution in cistanche supplementation? Test present pricing and availability under and join our Nootropics Depot information alerts:
Nootropics Depot CistaMAX – Optimized Cistanche – Offers and Value Drop Alerts
Get Value Alerts
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Disclosure: PricePlow depends on pricing from shops with which now we have a enterprise relationship. We work arduous to maintain pricing present, however you could discover a higher supply.
Posts are sponsored partly by the retailers and/or manufacturers listed on this web page.
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