The Superior Amino System That Absorbs When Others Cannot

Nutristat PÜRPEPTIDE combines PeptoPro hydrolyzed casein with vegan BCAAs for speedy amino acid supply throughout intense coaching. When your digestive system shuts down throughout laborious exercises, these peptides take up immediately by way of specialised transporters.

Most amino acid dietary supplements make daring claims about absorption and efficiency, however they’re constructed on a flawed basis. Free-form amino acids require digestion. BCAAs alone miss vital EAAs. And whenever you’re pushing laborious within the fitness center, your digestive system virtually shuts down as blood flows to working muscle tissue as a substitute of your intestine.

Nutristat solves these issues with PÜRPEPTIDE, a complicated amino formulation that mixes the breakthrough absorption know-how of PeptoPro hydrolyzed casein with a full spectrum of vegan fermented BCAAs. This is not simply one other amino product, it is a new mind-set about how amino acids must be delivered throughout intense coaching.

Like their game-changing PÜR NATIVE native whey protein that redefined protein purity, PÜRPEPTIDE continues Nutristat’s PÜR collection with one other uncompromising method to nutrient supply. The place PÜR NATIVE delivers superior post-workout restoration by way of cold-filtered native whey, PÜRPEPTIDE assaults the intra-workout window with peptides that take up when nothing else can.

What Makes PÜRPEPTIDE Totally different

The star of the present is PeptoPro, a extremely specialised protein hydrolysate that breaks casein down into di- and tri-peptides, that are chains of simply 2-3 amino acids. These tiny peptides bypass regular digestion totally, absorbing immediately by way of specialised transporters even when your digestive system is compromised throughout laborious coaching. (That is proper, Nutristat has been utilizing peptides since earlier than they had been “on development”.)

Whereas different amino dietary supplements sit in your abdomen ready to be processed, PÜRPEPTIDE’s peptides are already hitting your bloodstream.

Nutristat: Analysis. Purity. Efficiency.

Nutristat pairs this rapid-delivery system with 5 grams of vegan fermented BCAAs within the well-researched 2:1:1 ratio, making a dual-pathway method to amino acid supply. You get the speedy absorption of peptides plus the sustained launch of fermented BCAAs, guaranteeing your muscle tissue keep fed all through your total exercise.

Earlier than we dive into the whole ingredient breakdown, test our costs and join Nutristat information alerts:

PÜRPEPTIDE Substances

Every 9g scoop supplies:

• PeptoPro® Hydrolyzed Casein – 3g

  PeptoPro is not simply one other amino acid or protein powder, it is a extremely specialised casein hydrolysate engineered to resolve a elementary drawback in sports activities diet. Whereas conventional proteins require digestion earlier than absorption, PeptoPro comprises di- and tri-peptides (chains of simply 2-3 amino acids) that bypass the digestive course of totally. These peptides are so small they take up immediately by way of specialised transporters within the intestinal wall, delivering amino acids to muscle tissue even when your digestive system is basically shut down throughout intense train.

  The Train Digestion Downside

  Throughout intense train, your physique faces a vital dilemma. As train depth will increase, cardiac output will get redirected away from digestive organs towards working muscle tissue. At heavy train intensities, blood movement to digestive organs can drop to only 25% of resting ranges.^[1] This dramatic discount means intact proteins and even free amino acids sit unprocessed within the abdomen, unable to succeed in muscle tissue after they want them most.

  PeptoPro solves this by delivering pre-digested peptides that require no additional breakdown, due to an enzymatic hydrolysis course of that creates them.^[2] These molecules take up quicker than free amino acids by way of devoted peptide transporters, guaranteeing nutrient supply when conventional proteins would fail.

  Efficiency Enhancement Research

  The efficiency advantages of PeptoPro have been demonstrated in a number of human trials. In a biking time-trial research, Saunders and colleagues examined PeptoPro in opposition to carbohydrate alone in cyclists finishing simulated 60-km races. Whereas general instances confirmed modest variations, all efficiency enhancements occurred throughout the vital remaining phases — precisely when glycogen depletion makes amino acid availability essential.^[3]

  

  The CHO+PeptoPro group accomplished the ultimate 5-km climb 3% quicker (16.5 vs 16.9 minutes), with protein hydrolysate ingestion explaining a big proportion of efficiency variance in late-exercise segments. This enchancment occurred regardless of each teams receiving carbohydrate at maximal oxidation charges (~60g/hour), demonstrating PeptoPro’s advantages lengthen past easy caloric addition.

  Muscle Protein Synthesis Throughout Train

  Maybe PeptoPro’s most outstanding profit is its capability to stimulate muscle protein synthesis throughout train itself. Beelen and colleagues demonstrated that co-ingesting PeptoPro with carbohydrate throughout mixed endurance and resistance train created a constructive web protein stability (muscle constructing exceeded breakdown even whereas coaching).^[2]

  With out amino acid provision throughout train, the physique derives 5-15% of its power from amino acids, actually cannibalizing muscle tissue. PeptoPro supplementation reversed this catabolic state, shifting the stability towards anabolism (muscle constructing) even throughout intense coaching classes. This real-time muscle safety helps protect coaching variations and accelerates restoration.

  Restoration and Muscle Injury Safety

  PeptoPro’s advantages lengthen properly past the exercise window. The identical time-trial research that demonstrated efficiency enhancements additionally discovered important restoration benefits. Whereas the carbohydrate-only group skilled substantial will increase in creatine kinase (a marker of muscle harm) from 161 to 399 U/L, the PeptoPro group confirmed no important elevation (115 to 262 U/L).^[3]

  Muscle soreness rankings adopted the identical sample: considerably elevated with carbohydrate alone however not with PeptoPro. This safety in opposition to muscle harm interprets to quicker restoration between coaching classes and competitions.

  

  Enhanced Insulin Response and Nutrient Uptake

  PeptoPro triggers a extra sturdy insulin response than intact proteins. Analysis reveals whey protein hydrolysate will increase most plasma insulin focus by 28% in comparison with intact whey, leading to a 43% better space beneath the insulin curve.^[4] This enhanced insulin secretion accelerates glucose uptake and glycogen resynthesis, which is vital for speedy restoration between coaching classes or competitions.

  The mechanism includes elevated secretion of glucose-dependent insulinotropic polypeptide (GIP), which facilitates insulin launch from pancreatic beta-cells. Mixed with PeptoPro’s speedy amino acid supply, this creates an optimum hormonal setting for restoration and adaptation.

  The PeptoPro Benefit

  In contrast to theoretical advantages claimed by many dietary supplements, PeptoPro delivers measurable, sensible benefits rooted in its distinctive molecular construction. The di- and tri-peptide formulation ensures absorption when digestion is compromised, protects muscle tissue throughout coaching, enhances late-exercise efficiency, and accelerates restoration. For severe athletes pushing their limits, PeptoPro presents a scientifically validated resolution to the elemental problem of nutrient supply throughout intense train.

• Vegan Fermented BCAAs – 5g

  • L-Leucine – 2.5g
  • L-Isoleucine – 1.25g
  • L-Valine – 1.25g

  Whereas PeptoPro delivers rapid-absorbing peptides, PÜRPEPTIDE’s vegan fermented BCAAs present the three amino acids most important for muscle protein synthesis throughout coaching. This 2:1:1 ratio (leucine:isoleucine:valine) displays the pure composition present in muscle tissue and maximizes the anabolic signaling that happens when muscle tissue are beneath stress.

  

  The mTOR Connection

  Past serving as constructing blocks for protein, BCAAs are highly effective signaling molecules that flip the anabolic swap in muscle cells. Leucine acts as the first set off, activating mTORC1 (mechanistic goal of rapamycin advanced 1).^[5] Analysis reveals that BCAA ingestion following resistance train creates a extra pronounced mTORC1 response than leucine alone.^[6]

  Past Leucine: The Synergistic Trio

  Whereas leucine will get many of the consideration, isoleucine and valine aren’t simply alongside for the trip. Isoleucine independently enhances the method as properly.^[5] Valine helps preserve the amino acid pool throughout intense coaching, stopping the dramatic depletion that happens with leucine supplementation alone. This synergistic impact explains why full BCAA supplementation stimulates better myofibrillar protein synthesis than remoted leucine: the three work collectively to create an optimum anabolic setting.

  Metabolic Advantages Throughout Train

  BCAAs serve a novel metabolic position that turns into essential throughout intense coaching. In contrast to different amino acids that require liver processing, BCAAs are oxidized immediately in skeletal muscle, offering speedy power when glucose runs low.^[7] Throughout glycogen-depleted train, BCAA supplementation enhances train capability and will increase lipid oxidation, serving to athletes push by way of when power shops are compromised.^[8]

  The fermented supply issues too: fermentation produces ultra-pure amino acids with out the cruel chemical processing utilized in artificial manufacturing, leading to higher absorption and fewer digestive points throughout coaching.

• Antioxidant Mix – 150mg

  • Coffeeberry® Espresso Fruit Extract

    

    Coffeeberry brings the brain-boosting advantages of espresso polyphenols with out extreme stimulation. This standardized espresso fruit extract delivers concentrated chlorogenic acids (CGAs), the identical neuroprotective compounds that make espresso consumption helpful for cognitive well being, minus the excessive caffeine content material that may disrupt sleep or trigger jitters.

    A star compound in Coffeeberry is 5-caffeoylquinic acid (5-CQA), representing as much as 69% of the full chlorogenic acid content material relying on extraction strategies.^[9] This potent polyphenol prompts the Nrf2 pathway, a grasp regulator of mobile antioxidant defenses.^[10] By means of Nrf2 activation, 5-CQA upregulates protecting enzymes like heme oxygenase-1 and glutamate cysteine ligase, creating a strong defend in opposition to oxidative stress that may harm neurons and impair cognitive perform.

    Supporting Psychological Power and Focus

    Past antioxidant safety, espresso fruit extract helps cognitive efficiency by way of a number of mechanisms. Analysis reveals chlorogenic acids improve glucose metabolism, which is essential for sustaining regular mind power since neurons rely nearly solely on glucose for gas.^[11] Research have additionally recognized acetylcholinesterase inhibition as one other pathway, serving to protect acetylcholine ranges wanted for reminiscence and a spotlight.^[12]

    Nutristat acknowledges Coffeeberry’s worth — they’ve included it all through their lineup, from Pre Script pre-workout to this amino formulation. The antioxidant assist enhances PÜRPEPTIDE’s muscle safety technique, serving to neutralize the free radicals generated throughout intense coaching whereas supporting the psychological focus wanted to push by way of difficult exercises.

  • Freeze Dried Blueberry Powder

    

    Blueberries deliver severe antioxidant firepower to PÜRPEPTIDE by way of their wealthy anthocyanin content material. Greater than giving blueberries their deep blue/purple colour, they’re potent free radical scavengers that assist neutralize exercise-induced oxidative stress.^[13] Analysis reveals berry supplementation reduces markers of muscle harm and irritation following intense coaching, with athletes experiencing decrease creatine kinase ranges and lowered muscle soreness.^[14]

    The freeze-drying course of preserves blueberry’s bioactive compounds whereas concentrating their antioxidant capability. This implies you get the protecting advantages of recent blueberries in a steady, handy kind that mixes seamlessly into your intra-workout drink.

• Calci-Ok® Calcium Potassium Phosphate-Citrate

  Whereas amino acids steal the highlight in restoration formulation, Calci-Ok addresses a vital however neglected drawback: calcium losses throughout intense coaching. This specialised mineral advanced from Albion combines calcium, potassium, and phosphorus in a kind engineered for superior liquid dispersion and absorption, even when taken with milk-based proteins.

  Throughout vigorous train, you lose as much as 90mg of calcium by way of sweat in a single coaching session.^[15] This dermal calcium loss combines with exercise-induced metabolic acidosis to set off a cascade of issues: serum ionized calcium drops, parathyroid hormone (PTH) spikes by as much as 86%, and your physique begins breaking down bone tissue to take care of calcium homeostasis.^[16] With out intervention, you are actually cannibalizing your skeleton to gas your exercise.

  The inclusion of Calci-Ok helps defend in opposition to this calcium drain. In contrast to commonplace calcium dietary supplements that battle with absorption throughout train when blood movement diverts away from digestive organs, Calci-Ok maintains full dispersion in liquids at pH 3.5-8.0 with out requiring suspending brokers. This ensures constant calcium availability all through your exercise, serving to attenuate the PTH response and defend bone integrity when your physique wants it most.

The way to Use PÜRPEPTIDE

PÜRPEPTIDE shines brightest when used throughout your exercise. Combine one scoop with 6-8 ounces of water and sip all through your coaching session. The PeptoPro peptides take up quickly even whilst you’re coaching laborious, delivering amino acids when your digestive system is least able to processing common proteins.

For optimum anti-catabolic safety, you may also sip PÜRPEPTIDE between meals on relaxation days. The speedy absorption means you get an nearly speedy amino acid spike with out the digestive burden of complete proteins or the unfinished profile of standalone BCAAs.

Stacking Choices

PÜRPEPTIDE works exceptionally properly alongside different Nutristat merchandise:

• Pre-Exercise: Stack with PUMP SCRIPT liquid glycerol for enhanced hydration and pumps, or mix with Pre Script for full pre- and intra-workout assist
• Throughout Coaching: Proceed sipping PÜRPEPTIDE all through your exercise (including some PUMP SCRIPT may also be used intra-workout for sustained hyperhydration)
• Submit-Exercise: Comply with with PÜR NATIVE whey protein for full restoration
• Day by day Basis: Help your amino acid consumption with Nutristat’s Creapure® creatine for enhanced mobile power and muscle quantity (if not already utilizing Pre Script)

Flavors Obtainable

Conclusion: Amino Acids That Truly Work When You Want Them

PÜRPEPTIDE is not simply one other amino acid complement with a flowery title. It is constructed on real innovation in protein hydrolysis know-how that solves the elemental drawback of amino acid supply throughout train. Whereas rivals argue about BCAA ratios or free-form versus sure amino acids, Nutristat bypassed the complete debate by utilizing peptides that do not want digestion in any respect.

The inclusion of PeptoPro makes PÜRPEPTIDE distinctive within the amino acid class, they usually’ve been utilizing and educating about peptides since earlier than it was cool. This is not theoretical science or advertising and marketing hype, it is validated know-how that delivers amino acids when your physique is least able to processing them by way of regular channels. Mixed with a full dose of vegan BCAAs and performance-supporting antioxidants, PÜRPEPTIDE presents a whole intra-workout amino resolution that really works as marketed.

For athletes who’ve been disenchanted by the minimal outcomes from commonplace amino dietary supplements, PÜRPEPTIDE presents a scientifically superior different that delivers actual, measurable advantages whenever you want them most.